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Sodium Selenate 200 mcg x 100 capsules

Highlights

Serving Size 1 capsule
Amount per serving % DV
Selenium (as sodium selenate) 200 mcg 285
†   Daily Value not established
Other ingredients: Microcrystalline cellulose, Gelatin
Suggested Use: 1 capsule daily, or as directed by a health care professional.
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Overview

Selenium is a chemical element required in small amounts by most, and perhaps all, biological organisms. Selenium-containing antioxidant enzymes — such as the glutathione peroxidases (GPx) — help to rid the body of destructive peroxide and superoxide molecules. GPx enzymes are found in thyroid tissue and in many other parts of the body. Selenium deficiencies, and the resulting GPx shortages, therefore cause oxidative damage throughout the body.

Ailments that have been linked to low selenium levels include:

  • aging of skin, brain, and other tissues
  • age-related decline in performing mental tasks
  • celiac disease and intestinal damage
  • thyroid diseases
  • infertility in males and females
  • cancer
  • impaired bone metabolism, weakened bones, growth retardation
  • osteoarthritis
  • reduced immunity, susceptibility to infections
  • cardiovascular problems, blood clots, strokes, and atherosclerosis
  • Alzheimer’s and other neurological diseases
  • muscle pain, fatigue, proximal weakness
  • febrile seizures
  • some forms of mastitis
  • Buerger’s Disease
  • AIDS progression, if you have an HIV infection.

Selenium intake should be in the range of 55 to 400 mcg/day. This translates to 132 to 957 mcg/day of sodium selenate (about 1 to 5 capsules of LifeLink's product).

Sodium Selenate Monograph

Selenium is a chemical element that resembles the element sulfur in its properties, but with certain differences that make it biologically useful in its own right. Unlike sulfur, which is required in large amounts by all living things, selenium is only required in small amounts. In the body it is a component of at least 25 different proteins, including antioxidant enzymes, thyroid enzymes, and a number of proteins whose functions are still unknown.1

Selenium-containing antioxidant enzymes — such as the glutathione peroxidases (GPx) — help to rid the body of destructive peroxide and superoxide molecules by converting them to water and alcohol. GPx enzymes are found in thyroid tissue and in many other parts of the body — for example, the pancreas, testes, pituitary, eyes, and skin, as well as other tissues.2 Selenium deficiencies, and the resulting GPx shortages, therefore cause oxidative damage throughout the body.

What we can’t tell you

In the U.S. and some other industrialized countries, government agencies like the U.S. Food and Drug Administration have adopted censorship as a method for intensifying their control over the supplement industry and its customers. Thus, FDA regulations prohibit us from telling you that any of our products are effective as medical treatments, even if they are, in fact, effective.

Accordingly, we will limit our discussion of Sodium Selenate to a brief summary of relevant research, and let you draw your own conclusions about what medical conditions it may be effective in treating.

Causes of selenium deficiencies

Selenium deficiencies can be caused by insufficient selenium in the diet or by poor absorption in the digestive tract. Dietary deficiencies are less common than they used to be — thanks to supplementation — but absorption-related deficiencies are widespread. Poor selenium absorption may be caused by a number of medical conditions:3

  • celiac disease
  • Crohn’s disease
  • cystic fibrosis
  • pancreatic insufficiency
  • biliary atresia
  • liver disorders
  • cholestasis
  • the use of certain drugs.
Consequences of inadequate selenium in the body

Seleno-proteins are so important to the body’s well-being that low selenium status is a risk factor for many diseases.3 Ailments that have been linked to low selenium levels include:

  • aging due to peroxide damage4 or to telomere shortening5
  • age-related decline in performing mental tasks6
  • Buerger’s Disease (a serious vascular inflammation caused by tobacco)7
  • celiac disease 3
  • autoimmune thyroid diseases 3
  • intestinal damage3
  • infertility in males2
  • degeneration of ovaries2
  • cancer of the prostate2, digestive tract2,8,15, breast9, and lung2,10
  • weakened bones2
  • impaired bone metabolism, growth retardation2
  • osteoarthritis2
  • reduced immunity and UV protection in skin2
  • cardiovascular problems, thrombosis, and atherosclerosis2
  • Alzheimer’s11 and other neurological diseases17
  • muscle pain, fatigue, proximal weakness12
  • febrile seizures13
  • some forms of mastitis2
  • progression of HIV infection16
  • other infections2

An excellent review of the role and importance of selenium in the diet is the one by Stazi and Trinti (see page 392 of the reference).3

Let us look at two of these selenium deficiency problems.

Celiac disease

Celiac Disease is an inflammatory, auto-immune condition characterized by the inability to tolerate the protein gluten (found in grains such as wheat, oats, rye, and barley).14 People who have a genetic predisposition to the ailment, and whose diet includes gluten, experience effects ranging from fatigue to permanent damage to the intestine, thyroid, and other organs. Such damage can even trigger the formation of cancer tumors. When intestinal damage occurs, the absorption of food, vitamins and minerals is impaired. This leads to various deficiencies, including selenium deficiencies. A shortage of selenium exacerbates the inflammation and also allows the thyroid gland to be damaged by peroxides.3 Small wonder that celiac disease can be fatal.

While the proper treatment for this disease is a gluten-free diet, much of the disease’s secondary damage may be avoided if supplementary selenium is administered early enough.3

Thyroid ailments

Thyroid hormone synthesis requires continuous production of hydrogen peroxide.2 When allowed to run free, this highly destructive substance does serious damage to the body. But the body has an appropriate defense: antioxidative enzymes, including the GPx (glutathione peroxidase) enzymes. GPx enzymes require selenium as part of their structure. Without adequate supplies of selenium, the body fails to make enough GPx to control the peroxide, the peroxide escapes and does damage to nearly everything it touches — particularly to the tissue of the thyroid gland itself. The resulting thyroid malfunctions can lead to various diseases.

Such thyroid problems are easy to avoid. As Stazi and Trinti state in their review, “… an adequate selenium intake is needed to maximize the activity of gluathione peroxidase (GPx) and other selenoproteins.”3

Dosage

Selenium intake should typically be in the range of 55 to 400 mcg per day.3 This translates to 132 to 957 mcg/day of selenium selenate. Both excess and deficiency of selenium can cause impaired growth.2,8 Amounts greater than 800 mcg/day of selenium (1914 mcg/day of sodium selenate), if consumed routinely, may lead to undesirable side effects, such as impaired growth of hair, fingernails, and other fast-growing tissues.8

Conclusion

Are Sodium Selenate supplements useful for the conditions and purposes mentioned above? We aren’t allowed to tell you, so you should take a look at some of the references cited here, and then decide for yourself.

References
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